publication . Article . 2014

АУТОАНТИТЕЛА К ДЕКАРБОКСИЛАЗЕ ГЛЮТАМИНОВОЙ КИСЛОТЫ КАК ПАТОГЕНЕТИЧЕСКИЙ МАРКЕР САХАРНОГО ДИАБЕТА 1 ТИПА

Array В. Карпович; Array И. Бураковский; Array В. Пивень; Array Н. Лухверчик; Array В. Полегенькая;
Open Access
  • Published: 22 Jul 2014 Journal: Medical Immunology (Russia), volume 13, page 257 (issn: 1563-0625, eissn: 2313-741X, Copyright policy)
  • Publisher: SPb RAACI
Abstract
Abstract . A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. ( Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260 )
Subjects
free text keywords: autoantibodies, glutamic acid decarboxylase, Immunologic diseases. Allergy, RC581-607, Immunoenzyme assay, Predictive marker, Diagnostic Reagent, Diabetes mellitus, medicine.disease, medicine, Pathogenesis, Immunology, Endocrinology, medicine.medical_specialty, Internal medicine, Autoantibody, Type 1 diabetes, Glutamate decarboxylase, business.industry, business
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