publication . Article . 2014

AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS

N. V. Piven; L. N. Lukhverchyk; A. I. Burakovsky; N. V. Polegenkaya; M. V. Karpovich;
Open Access Russian
  • Published: 01 Jul 2014 Journal: Medicinskaâ Immunologiâ (issn: 1563-0625, eissn: 2313-741X, Copyright policy)
  • Publisher: SPb RAACI
Abstract
Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)
doi: 10.15789/1563-0625-2011-2-3-257-260
Subjects
free text keywords: autoantibodies, glutamic acid decarboxylase, immunoenzyme assay, diabetes mellitus, pathogenesis, Immunologic diseases. Allergy, RC581-607
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Medicinskaâ Immunologiâ
Article . 2014
Provider: DOAJ-Articles
SPb RAACI/ Medicinskaâ Immunologiâ
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