Efficient and Cost-Effective Generation of Mature Neurons From Human Induced Pluripotent Stem Cells

Article, Other literature type English OPEN
Badja , Cherif ; Maleeva , Galyna ; El-Yazidi , Claire ; Barruet , Emilie ; Lasserre , Manon ; Tropel , Philippe ; Binetruy , Bernard ; Bregestovski , Piotr ; Magdinier , Frédérique (2014)
  • Publisher: HAL CCSD
  • Related identifiers: doi: 10.5966/sctm.2014-0024, pmc: PMC4250204
  • Subject: [ SDV.GEN.GH ] Life Sciences [q-bio]/Genetics/Human genetics | Enabling Technologies for Cell-Based Clinical Translation
    mesheuropmc: nervous system

The authors describe a feeder-free method of generating induced pluripotent stem cells by relying on the use of a chemically defined medium that overcomes the need for embryoid body formation and neuronal rosette isolation for neuronal precursors and terminally differen... View more
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