Efficient and Cost-Effective Generation of Mature Neurons From Human Induced Pluripotent Stem Cells

Article, Other literature type English OPEN
Badja, Cherif; Maleeva, Galyna; El-Yazidi, Claire; Barruet, Emilie; Lasserre, Manon; Tropel, Philippe; Binetruy, Bernard; Bregestovski, Piotr; Magdinier, Frédérique;
  • Publisher: AlphaMed Press
  • Related identifiers: doi: 10.5966/sctm.2014-0024, pmc: PMC4250204
  • Subject: [ SDV.GEN.GH ] Life Sciences [q-bio]/Genetics/Human genetics | Enabling Technologies for Cell-Based Clinical Translation
    mesheuropmc: nervous system

The authors describe a feeder-free method of generating induced pluripotent stem cells by relying on the use of a chemically defined medium that overcomes the need for embryoid body formation and neuronal rosette isolation for neuronal precursors and terminally differen... View more
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