TGF-β and Insulin Signaling Regulate Reproductive Aging via Oocyte and Germline Quality Maintenance

Article, Other literature type English OPEN
Luo, Shijing; Kleemann, Gunnar A.; Ashraf, Jasmine M.; Shaw, Wendy M.; Murphy, Coleen T.;
(2010)

Reproductive cessation is perhaps the earliest aging phenotypes humans experience. Similarly, C. elegans’ reproduction ceases in mid-adulthood. Although somatic aging has been studied in both worms and humans, mechanisms regulating reproductive aging are not yet underst... View more
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