The antibiotic resistance “mobilome”: searching for the link between environment and clinic

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Perry, Julie A.; Wright, Gerard D.;

Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia. The environmental “resistome” is the collection of all genes that directly or indirectly contribute to ... View more
  • References (60)
    60 references, page 1 of 6

    Allen H. K. Looft T. Bayles D. O. Humphrey S. Levine U. Y. Alt D. (2011). Antibiotics in feed induce prophages in swine fecal microbiomes. MBio 2 e00260-11. 10.1128/mBio.00260-11

    Amann R. I. Ludwig W. Schleifer K. H. (1995). Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol. Rev. 59 143–169.

    Aminov R. I. (2011). Horizontal gene exchange in environmental microbiota. Front. Microbiol. 2:158. 10.3389/fmicb.2011.00158

    Aminov R. I. Mackie R. I. (2007). Evolution and ecology of antibiotic resistance genes. FEMS Microbiol. Lett. 271 147–161.

    Avery O. T. Macleod C. M. Mccarty M. (1944). Studies on the chemical nature of the substance inducing transformation of pneumococcal types: in duction of transformation by a desoxyribonucleic acid fraction isolated from Pneumococcus type III. J. Exp. Med. 79 137–158. 10.1084/jem.79.2.137

    Baquero F. Martinez J. L. Canton R. (2008). Antibiotics and antibiotic resistance in water environments. Curr. Opin. Biotechnol. 19 260–265. 10.1016/j.copbio.2008.05.006

    Barlow M. (2009). What antimicrobial resistance has taught us about horizontal gene transfer. Methods Mol. Biol. 532 397–411. 10.1007/978-1-60327-853-9_23

    Benveniste R. Davies J. (1973). Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Proc. Natl. Acad. Sci. U.S.A. 70 2276–2280. 10.1073/pnas.70.8.2276

    Burke J. Schneider D. Westpheling J. (2001). Generalized transduction in Streptomyces coelicolor. Proc. Natl. Acad. Sci. U.S.A. 98 6289–6294. 10.1073/pnas.101589398

    Chen I. Christie P. J. Dubnau D. (2005). The ins and outs of DNA transfer in bacteria. Science 310 1456–1460. 10.1126/science.1114021

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