publication . Article . 2016

Effect of Exercise and Calorie Restriction on Tissue Acylcarnitines, Tissue Desaturase Indices, and Fat Accumulation in Diet-Induced Obese Rats

Adonsia Yating Yang; Manami Kaneko; K. N. Bhanu Prakash; Suresh Anand Sadananthan; Bin Zhu; Megumi Hirayama; Venkatesh Gopalan; Yoshinori Satomi; Takashi Horiguchi; Seigo Ishino; ...
Open Access English
  • Published: 01 May 2016
Both exercise and calorie restriction interventions have been recommended for inducing weight-loss in obese states. However, there is conflicting evidence on their relative benefits for metabolic health and insulin sensitivity. This study seeks to evaluate the differential effects of the two interventions on fat mobilization, fat metabolism, and insulin sensitivity in diet-induced obese animal models. After 4 months of ad libitum high fat diet feeding, 35 male Fischer F344 rats were grouped (n = 7 per cohort) into sedentary control (CON), exercise once a day (EX1), exercise twice a day (EX2), 15% calorie restriction (CR1) and 30% calorie restriction (CR2) cohort...
free text keywords: Article, Multidisciplinary, Biology, Cohort, Adipose tissue, Endocrinology, medicine.medical_specialty, medicine, Calorie restriction, Carnitine, medicine.drug, Obesity, medicine.disease, Insulin resistance, Lipid metabolism, Diet-induced obese, Internal medicine
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