Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages.

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Chow, ML; Pramparo, T; Winn, ME; Barnes, CC; Li, HR; Weiss, L; Fan, JB; Murray, S; April, C; Belinson, H; Fu, XD; Wynshaw-Boris, A; Schork, NJ; Courchesne, E;

Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression studies have not id... View more