Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer

Article English OPEN
de Heer, Pieter; Sandel, Maro H.; Guertens, Gunther; de Boeck, Gert; Koudijs, Margaretha M.; Nagelkerke, J. Fred; Junggeburt, Jan M. C.; de Bruijn, Ernst A.; van de Velde, Cornelis J. H.; Kuppen, Peter J. K.;
  • Publisher: Springer Nature
  • Journal: Cancer Chemotherapy and Pharmacology,volume 62,issue 5,pages811-819 (issn: 0344-5704, eissn: 1432-0843)
  • Related identifiers: pmc: PMC2516537, doi: 10.1007/s00280-007-0668-4
  • Subject: Toxicology | Original Article | Immune response | Celecoxib | Cyclooxygenase-2 | Pharmacology | Prostaglandins | Pharmacology (medical) | Cancer Research | Oncology | CC531 rat colon tumor liver metastases model
    mesheuropmc: musculoskeletal diseases

Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce the risk of colorectal cancer in cyclooxygenase-2 (COX-2) overexpressing colorectal cancers. The present study was designed to evaluate the inhibitory effects of the COX-2 inhibitor cel... View more
Share - Bookmark