Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer

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de Heer, Pieter ; Sandel, Maro H. ; Guertens, Gunther ; de Boeck, Gert ; Koudijs, Margaretha M. ; Nagelkerke, J. Fred ; Junggeburt, Jan M. C. ; de Bruijn, Ernst A. ; van de Velde, Cornelis J. H. ; Kuppen, Peter J. K. (2008)
  • Publisher: Springer Nature
  • Journal: Cancer Chemotherapy and Pharmacology, volume 62, issue 5, pages 811-819 (issn: 0344-5704, eissn: 1432-0843)
  • Related identifiers: pmc: PMC2516537, doi: 10.1007/s00280-007-0668-4
  • Subject: Toxicology | Original Article | Immune response | Celecoxib | Cyclooxygenase-2 | Pharmacology | Prostaglandins | Pharmacology (medical) | Cancer Research | Oncology | CC531 rat colon tumor liver metastases model
    mesheuropmc: musculoskeletal diseases

Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce the risk of colorectal cancer in cyclooxygenase-2 (COX-2) overexpressing colorectal cancers. The present study was designed to evaluate the inhibitory effects of the COX-2 inhibitor cel... View more
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