publication . Article . 2017

Biomimetic strategies for fracture repair: engineering the cell microenvironment for directed tissue formation

Vas, Wollis J; Shah, Mittal; Al Hosni, Rawiya; Owen, Helen C; Roberts, Scott J;
Open Access English
  • Published: 01 Apr 2017 Journal: Journal of Tissue Engineering, volume 8 (issn: 2041-7314, eissn: 2041-7314, Copyright policy)
  • Publisher: SAGE Journals
Abstract
Complications resulting from impaired fracture healing have major clinical implications on fracture management strategies. Novel concepts taken from developmental biology have driven research strategies towards the elaboration of regenerative approaches that can truly harness the complex cellular events involved in tissue formation and repair. Advances in polymer technology and a better understanding of naturally derived scaffolds have given rise to novel biomaterials with an increasing ability to recapitulate native tissue environments. This coupled with advances in the understanding of stem cell biology and technology has opened new avenues for regenerative st...
Subjects
free text keywords: Special Issue Article, stem cells, QD415-436, Fracture repair, biomimetic, Biochemistry, endochondral ossification, biomaterials
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publication . Article . 2017

Biomimetic strategies for fracture repair: engineering the cell microenvironment for directed tissue formation

Vas, Wollis J; Shah, Mittal; Al Hosni, Rawiya; Owen, Helen C; Roberts, Scott J;