Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway

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Lee, Heung-Man ; Kang, Ju-Hyung ; Shin, Jae-Min ; Lee, Seoung-Ae ; Park, Il-Ho (2017)
  • Publisher: Hindawi
  • Journal: Mediators of Inflammation, volume 2,017 (issn: 0962-9351, eissn: 1466-1861)
  • Related identifiers: pmc: PMC5540463, doi: 10.1155/2017/8123281
  • Subject: RB1-214 | Pathology | Research Article | Article Subject
    mesheuropmc: respiratory system

Epithelial-mesenchymal transition (EMT) is a biological process that allows epithelial cells to assume a mesenchymal cell phenotype. EMT is considered as a therapeutic target for several persistent inflammatory airway diseases related to tissue remodeling. Herein, we in... View more
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