Probiotic lactic acid bacteria – the fledgling cuckoos of the gut?

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Berstad, Arnold; Raa, Jan; Midtvedt, Tore; Valeur, Jørgen;

It is tempting to look at bacteria from our human egocentric point of view and label them as either ‘good’ or ‘bad’. However, a microbial society has its own system of government – ‘microcracy’ – and its own rules of play. Lactic acid bacteria are often referred to as r... View more
  • References (42)
    42 references, page 1 of 5

    1. Servin AL. Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens. FEMS Microbiol Rev 2004; 28: 405 40.

    2. Di Cerbo A, Palmieri B, Aponte M, Morales-Medina JC, Iannitti T. Mechanisms and therapeutic effectiveness of lactobacilli. J Clin Pathol 2016; 69: 187 203.

    3. Berstad A, Hauso O, Valeur J. Intestinal staphylococcal small colony variants: a cause of medically unexplained physical symptoms? Microb Ecol Health Dis 2014; 25: 25817. doi:

    4. Voltan S, Martines D, Elli M, Brun P, Longo S, Porzionato A, et al. Lactobacillus crispatus M247-derived H2O2 acts as a signal transducing molecule activating peroxisome proliferator activated receptor-gamma in the intestinal mucosa. Gastroenterology 2008; 135: 1216 27.

    5. Tan J, McKenzie C, Potamitis M, Thorburn AN, Mackay CR, Macia L. The role of short-chain fatty acids in health and disease. Adv Immunol 2014; 121: 91 119.

    6. Bennet SM, Ohman L, Simren M. Gut microbiota as potential orchestrators of irritable bowel syndrome. Gut Liver 2015; 9: 318 31.

    7. Balsari A, Ceccarelli A, Dubini F, Fesce E, Poli G. The fecal microbial population in the irritable bowel syndrome. Microbiologica 1982; 5: 185 94.

    8. Campbell AK, Matthews SB, Vassel N, Cox CD, Naseem R, Chiachi J, et al. Bacterial metabolic 'toxins': a new mechanism for lactose and food intolerance, and irritable bowel syndrome. Toxicology 2010; 278: 268 76.

    9. Raa J, Berstad A, Valeur J. Forstyrrelser i tarmkanalens redoks-biologi en oversett sykdomsmekanisme? NGF-nytt 2015; 22: 32 6.

    10. Saez-Lara MJ, Gomez-Llorente C, Plaza-Diaz J, Gil A. The role of probiotic lactic acid bacteria and bifidobacteria in the prevention and treatment of inflammatory bowel disease and other related diseases: a systematic review of randomized human clinical trials. Biomed Res Int 2015; 2015: 505878.

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