Widespread Genomic Incompatibilities in Caenorhabditis elegans

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Snoek, L.B.; Orbidans, H.E.; Stastna, J.; Aartse, A.; Rodriguez Sanchez, M.; Riksen, J.A.G.; Kammenga, J.E.; Harvey, S.C.;
  • Publisher: Genetics Society of America
  • Journal: G3: Genes|Genomes|Genetics,volume 4,issue 10,pages1,813-1,823 (eissn: 2160-1836)
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  • Related identifiers: doi: 10.1534/g3.114.013151, pmc: PMC4199689
  • Subject: Bateson-Dobzhansky-Muller | synthetic lethals | cryptic genetic-variation | QTL | outbreeding depression | Investigations | reproductive isolation | hybrid sterility | c. elegans | natural variation data | introgression line | life-history traits | tribolium-castaneum | population-genetics | negative epistasis

In the Bateson-Dobzhansky-Muller (BDM) model of speciation, incompatibilities emerge from the deleterious interactions between alleles that are neutral or advantageous in the original genetic backgrounds, i.e., negative epistatic effects. Within species such interaction... View more