Widespread Genomic Incompatibilities in Caenorhabditis elegans

Article English OPEN
Snoek, L.B.; Orbidans, H.E.; Stastna, J.; Aartse, A.; Rodriguez Sanchez, M.; Riksen, J.A.G.; Kammenga, J.E.; Harvey, S.C.;
(2014)
  • Publisher: Genetics Society of America
  • Journal: G3: Genes|Genomes|Genetics,volume 4,issue 10,pages1,813-1,823 (eissn: 2160-1836)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1534/g3.114.013151, pmc: PMC4199689
  • Subject: Bateson-Dobzhansky-Muller | synthetic lethals | cryptic genetic-variation | QTL | outbreeding depression | Investigations | reproductive isolation | hybrid sterility | c. elegans | natural variation data | introgression line | life-history traits | tribolium-castaneum | population-genetics | negative epistasis

In the Bateson-Dobzhansky-Muller (BDM) model of speciation, incompatibilities emerge from the deleterious interactions between alleles that are neutral or advantageous in the original genetic backgrounds, i.e., negative epistatic effects. Within species such interaction... View more