Profiling and Distribution of Metabolites of Procyanidin B2 in Mice by UPLC-DAD-ESI-IT-TOF-MSn Technique

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Xiao, Ying ; Hu, Zhongzhi ; Yin, Zhiting ; Zhou, Yiming ; Liu, Taiyi ; Zhou, Xiaoli ; Chang, Dawei (2017)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Pharmacology, volume 8 (issn: 1663-9812, eissn: 1663-9812)
  • Related identifiers: doi: 10.3389/fphar.2017.00231/full, doi: 10.3389/fphar.2017.00231, pmc: PMC5415559
  • Subject: identification | RM1-950 | Therapeutics. Pharmacology | metabolic profile | Pharmacology | Original Research | procyanidin B2 | UPLC-DAD-ESI -IT-TOF-MSn | distribution

The metabolite profiles and distributions of procyanidin B2 were qualitatively described using UPLC-DAD-ESI-IT-TOF-MSn without help of reference standards, and a possible metabolic pathway was proposed in the present study. Summarily, 53 metabolites (24 new metabolites)... View more
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