Targeted Delivery of siRNA to Macrophages for Anti-inflammatory Treatment
Article, Other literature type
- Publisher: Nature Publishing Group
Molecular Biology | Genetics | Drug Discovery | Pharmacology | Original Articles | Molecular Medicine
Inflammation mediated by tumor necrosis factor-α (TNF-α) and the associated neuronal apoptosis characterizes a number of neurologic disorders. Macrophages and microglial cells are believed to be the major source of TNF-α in the central nervous system (CNS). Here, we sho...