Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells

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Zhang, Xiaowei; Wu, Shili; Naccarato, Ty; Prakash-Damani, Manan; Chou, Yuan; Chu, Cong-Qiu; Zhu, Yong;
(2017)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 12,issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0180138, pmc: PMC5493350
  • Subject: Cell Membranes | Research Article | Chondrocytes | Anatomy | Staining | Tissue Repair | Cytoplasmic Staining | Safranin Staining | Biological Tissue | Connective Tissue | Collagens | Proteins | Articular Cartilage | Cellular Types | Stem Cells | Biology and Life Sciences | Cartilage | Research and Analysis Methods | Physiology | Medicine | Animal Cells | Connective Tissue Cells | Specimen Preparation and Treatment | Q | R | Cell Biology | Cellular Structures and Organelles | Mesenchymal Stem Cells | Science | Biochemistry | Medicine and Health Sciences | Physiological Processes

Microfracture, a common procedure for treatment of cartilage injury, induces fibrocartilage repair by recruiting bone marrow derived mesenchymal stem cells (MSC) to the site of cartilage injury. However, fibrocartilage is inferior biomechanically to hyaline cartilage. S... View more
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