Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector

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Sasaki, Makoto; Mathis, J Michael; Jennings, Merilyn H; Jordan, Paul; Wang, Yuping; Ando, Tomoaki; Joh, Takashi; Alexander, J Steven;
  • Publisher: BioMed Central
  • Journal: Journal of Inflammation (London, England),volume 2,pages13-13 (issn: 1476-9255, eissn: 1476-9255)
  • Related identifiers: doi: 10.1186/1476-9255-2-13, pmc: PMC1291390
  • Subject: RM1-950 | Therapeutics. Pharmacology | Research

<p>Abstract</p> <p>Genetic deficiency in the expression of interleukin-10 (IL-10) is associated with the onset and progression of experimental inflammatory bowel disease (IBD). The clinical significance of IL-10 expression is supported by studies showing that immune-aug... View more
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