A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus

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Owens, RA; Hammel, S; Sheridan, KJ; Jones, GW; Doyle, S;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 9,issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4157829, doi: 10.1371/journal.pone.0106942
  • Subject: Microbial Pathogens | Biotechnology | Biology | Research Article | Biology and Life Sciences | Microbiology | Medicine | Applied Microbiology | Q | Medical Microbiology | R | Fungal Biochemistry | Science | Aspergillus Fumigatus | Fungal Pathogens | Mycology

A combined proteomics and metabolomics approach was utilised to advance the identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here, implementation of a shotgun proteomic strategy led to the identification of non-redundant mycelial pr... View more
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