Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti.
Octávio A C Talyuli
Thiago M Venancio
Ana C Bahia
Marcos H Sorgine
Pedro L Oliveira
Gabriela O Paiva-Silva
- Publisher: Public Library of Science (PLoS)
(issn: 1932-6203, eissn: 1932-6203)
Q | R | Research Article | Science | Medicine
Blood-feeding mosquitoes are exposed to high levels of heme, the product of hemoglobin degradation. Heme is a pro-oxidant that influences a variety of cellular processes. We performed a global analysis of heme-regulated Aedes aegypti (yellow fever mosquito) transcriptio...