Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy
- Publisher: Hindawi Publishing Corporation
Stem Cells International,
(issn: 1687-966X, eissn: 1687-9678)
Research Article | Internal medicine | amniotic fluid ; mesenchymal stem cells ; epigenetics | RC31-1245 | Article Subject
mesheuropmc: embryonic structures
Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. However, MSCs undergo replicative senescence. So far, the mole...