Characterization of the genetic variation present in CYP3A4 in three South African populations

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Britt Ingrid Drögemöller; Marieth ePlummer; Lundi eKorkie; Gloudi eAgenbag; Anke eDunaiski; Dana eNiehaus; Liezl eKoen; Stefan eGebhardt; Nicol eSchneider; Antonel eOlckers; Galen eWright; Louise eWarnich;

TThe CYP3A4 enzyme is the most abundant human cytochrome P450 and is regarded as the most important enzyme involved in drug metabolism. Inter-individual and inter-population variability in gene expression and enzyme activity are thought to be influenced, in part, by gen... View more
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