Characterization of the genetic variation present in CYP3A4 in three South African populations

Article English OPEN
Drögemöller, Britt ; Plummer, Marieth ; Korkie, Lundi ; Agenbag, Gloudi ; Dunaiski, Anke ; Niehaus, Dana ; Koen, Liezl ; Gebhardt, Stefan ; Schneider, Nicol ; Olckers, Antonel ; Wright, Galen ; Warnich, Louise (2013)

TThe CYP3A4 enzyme is the most abundant human cytochrome P450 and is regarded as the most important enzyme involved in drug metabolism. Inter-individual and inter-population variability in gene expression and enzyme activity are thought to be influenced, in part, by gen... View more
Share - Bookmark