Characterization of the genetic variation present in CYP3A4 in three South African populations
- Publisher: Frontiers Media S.A.
Frontiers in Genetics,
(issn: 1664-8021, eissn: 1664-8021)
CYP3A4 | QH426-470 | mixed ancestry | Genetics | Xhosa | Pharmacology | Original Research Article | Khoisan | South African populations | pharmacogenetics
TThe CYP3A4 enzyme is the most abundant human cytochrome P450 and is regarded as the most important enzyme involved in drug metabolism. Inter-individual and inter-population variability in gene expression and enzyme activity are thought to be influenced, in part, by gen...