Modelling Toehold-Mediated RNA Strand Displacement

Article, Other literature type, Preprint English OPEN
Šulc, Petr ; Ouldridge, Thomas E. ; Romano, Flavio ; Doye, Jonathan P.K. ; Louis, Ard A. (2015)
  • Publisher: The Biophysical Society
  • Journal: Biophysical Journal, volume 108, issue 5, pages 1,238-1,247 (issn: 0006-3495)
  • Related identifiers: pmc: PMC4375624, doi: 10.1016/j.bpj.2015.01.023
  • Subject: Physics - Chemical Physics | Quantitative Biology - Biomolecules | Proteins and Nucleic Acids | Physics - Biological Physics | Biophysics | Condensed Matter - Soft Condensed Matter

We study the thermodynamics and kinetics of an RNA toehold-mediated strand displacement reaction with a recently developed coarse-grained model of RNA. Strand displacement, during which a single strand displaces a different strand previously bound to a complementary sub... View more
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