International audience; Animal studies have suggested neuropeptide S (NPS) and its receptor (NPSR) to be involved in the pathogenesis of anxiety-related behavior. In the present study, a multilevel approach was applied to further elucidate the role of NPS in the etiolog... View more
1 Department of Psychiatry, University of Muenster, 2 Department of Psychiatry, University of Wuerzburg, 3 Institute of Psychology, University of Greifswald, 4 Institute of Psychology, University of Muenster, 5 Department of Radiology, University of Muenster, 6 Department of Psychiatry, University of Bonn, 7 Department of Psychiatry, University of Frankfurt, 8 Department of Psychiatry, University of Goettingen, 9 Institute of Transfusion Medicine and Transplantation Immunology, University of Muenster, 10 Max-Planck-Institute of Psychiatry, Munich, 11 Institute of Clinical Psychology and Psychotherapy, University of Koeln, 12 Department of Psychiatry, University of Marburg, 13 Christoph-Dornier-Foundation for Clinical Psychology, Bremen, 14 Zentrum für Klinische Psychologie und Rehabilitation, University of Bremen, 15 Department of Psychology, University of Wuerzburg, 16 Department of Psychiatry, Charité, Berlin, 17 Institute of Psychology, University of Berlin, 18 Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany [INSERT TABLE 1 ABOUT HERE] [INSERT FIGURE 2 ABOUT HERE] [INSERT FIGURE 3 ABOUT HERE]
10. Meis S, Bergado-Acosta JR, Yanagawa Y, Obata K, Stork O, Munsch T. Identification of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus. PLoS One 2008; 3: e2695.
11. Pape HC, Jüngling K, Seidenbecher T, Lesting J, Reinscheid RK. Neuropeptide S: A transmitter system in the brain regulating fear and anxiety. Neuropharmacology. (in press).
12. LeDoux JE. Emotion circuits in the brain. Annu Rev Neurosci 2000; 23: 155-184.
13. Phillips ML, Drevets WC, Rauch SL, Lane R. Neurobiology of emotion perception I: The neural basis of normal emotion perception. Biol Psychiatry 2003; 54: 504-514.
14. Phillips ML, Drevets WC, Rauch SL, Lane R. Neurobiology of emotion perception II: Implications for major psychiatric disorders. Biol Psychiatry 2003; 54: 515-528.
15. Etkin A, Klemenhagen KC, Dudman JT, Rogan MT, Hen R, Kandel ER et al. Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron 2004; 44: 1043-1055.
16. Javanmard M, Shlik J, Kennedy SH, Vaccarino FJ, Houle S, Bradwejn J. Neuroanatomic correlates of CCK-4-induced panic attacks in healthy humans: a comparison of two time points. Biol Psychiatry 1999; 45: 872-882.
17. Pfleiderer B, Zinkirciran S, Arolt V, Heindel W, Deckert J, Domschke K. fMRI amygdala activation during a spontaneous panic attack in a patient with panic disorder. World J Biol Psychiatry 2007; 8: 269-272.
18. Sakai Y, Kumano H, Nishikawa M, Sakano Y, Kaiya H, Imabayashi E et al. Cerebral glucose metabolism associated with a fear network in panic disorder. Neuroreport 2005; 16: 927-931.