Biological Evaluation and Molecular Dynamics Simulation of Chalcone Derivatives as Epidermal Growth Factor-Tyrosine Kinase Inhibitors

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Sangpheak, Kanyani; Tabtimmai, Lueacha; Seetaha, Supaphorn; Rungnim, Chompoonut; Chavasiri, Warinthorn; Wolschann, Peter; Choowongkomon, Kiattawee; Rungrotmongkol, Thanyada;

Targeted cancer therapy has become a high potential cancer treatment. Epidermal growth factor receptor (EGFR), which plays an important role in cell signaling, enhanced cell survival and proliferation, has been suggested as molecular target for the development of novel ... View more
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