Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus

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Laustsen, Andreas H.; Engmark, Mikael; Clouser, Christopher; Timberlake, Sonia; Vigneault, Francois; Gutiérrez, José María; Lomonte, Bruno;
(2017)
  • Publisher: PeerJ Inc.
  • Journal: PeerJ,volume 5 (issn: 2167-8359, eissn: 2167-8359)
  • Related identifiers: pmc: PMC5267563, doi: 10.7717/peerj.2924
  • Subject: Toxicology | Biotechnology | antibody | Antivenom | Snake venom | Coral snake | Medicine | Synthetic Biology | Murine immune response | Micrurus nigrocinctus | R | Venom | Toxins | Bioinformatics | Transcriptomics | Antibody isotyping | Antibodies | Micrurus | Immunology | High-throughput sequencing
    mesheuropmc: complex mixtures

Snakebite envenomings represent a neglected public health issue in many parts of the rural tropical world. Animal-derived antivenoms have existed for more than a hundred years and are effective in neutralizing snake venom toxins when timely administered. Howeve... View more