The Episode of Genetic Drift Defining the Migration of Humans out of Africa Is Derived from a Large East African Population Size

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Elhassan, Nuha; Gebremeskel, Eyoab Iyasu; Elnour, Mohamed Ali; Isabirye, Dan; Okello, John; Hussien, Ayman; Kwiatksowski, Dominic; Hirbo, Jibril; Tishkoff, Sara; Ibrahim, Muntaser E.;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 9,issue 5 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4028218, doi: 10.1371/journal.pone.0097674
  • Subject: Molecular Biology | Population Genetics | Sequencing Techniques | Research Article | Biology and Life Sciences | Genetic Drift | Medicine | Evolutionary Processes | Ecological Metrics | Population Size | Evolutionary Genetics | Q | Effective Population Size | Mutation | R | Ecology | Haplotypes | Evolutionary Biology | Genetics | Molecular Biology Techniques | Science | Sequence Analysis

Human genetic variation particularly in Africa is still poorly understood. This is despite a consensus on the large African effective population size compared to populations from other continents. Based on sequencing of the mitochondrial Cytochrome C Oxidase subunit II ... View more
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