Parameters influencing the introduction of plasmid DNA into cells by the use of synthetic amphiphiles as a carrier system

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van der Woude, I; Visser, H W; ter Beest, M B; Wagenaar, A; Ruiters, M H; Engberts, J B; Hoekstra, D;
(1995)
  • Publisher: Elsevier BV
  • Journal: Biochimica et Biophysica Acta (BBA) - Biomembranes, volume 1,240, issue 1, pages 34-40 (issn: 0005-2736)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1016/0005-2736(95)00161-1
  • Subject: CATIONIC AMPHIPHILES | TRANSFECTION | SYNTHETIC AMPHIPHILE | DOTMA | VESICLES | ASYMMETRIC FUSION | CARRIER | Cell Biology | COS-7 | Biochemistry | MAMMALIAN-CELLS | Biophysics | PHYSICOCHEMICAL CHARACTERISTICS

Parameters that affect cellular transfection as accomplished by introducing DNA via carriers composed of cationic synthetic amphiphiles, have been investigated with the aim to obtain insight into the mechanism of DNA translocation. Such insight may be exploited in optim... View more
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