Vildagliptin Can Alleviate Endoplasmic Reticulum Stress in the Liver Induced by a High Fat Diet

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Ma, Xiaoqing ; Du, Wenhua ; Shao, Shanshan ; Yu, Chunxiao ; Zhou, Lingyan ; Jing, Fei (2018)
  • Publisher: Hindawi
  • Journal: BioMed Research International, volume 2,018 (issn: 2314-6133, eissn: 2314-6141)
  • Related identifiers: pmc: PMC5867538, doi: 10.1155/2018/5045182
  • Subject: R | Research Article | Medicine | Article Subject

Purpose. We investigated whether a DDP-4 inhibitor, vildagliptin, alleviated ER stress induced by a high fat diet and improved hepatic lipid deposition. Methods. C57BL/6 mice received standard chow diet (CD), high fat diet (HFD), and HFD administered with vildagliptin (... View more
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