Protective Effects of Total Saponins of Aralia elata (Miq.) on Endothelial Cell Injury Induced by TNF-α via Modulation of the PI3K/Akt and NF-κB Signalling Pathways

Other literature type, Article English OPEN
Zhou, Ping; Xie, Weijie; Luo, Yun; Lu, Shan; Dai, Ziru; Wang, Ruiying; Sun, Guibo; Sun, Xiaobo;
  • Publisher: Multidisciplinary Digital Publishing Institute
  • Journal: International Journal of Molecular Sciences,volume 20,issue 1 (issn: 1422-0067, eissn: 1422-0067)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.3390/ijms20010036, pmc: PMC6337668
  • Subject: atherosclerosis | endothelial cell injury | Chemistry | tumour necrosis factor α | QD1-999 | apoptosis | total saponins of <i>Aralia elata</i> (Miq.) Seem. | Article | QH301-705.5 | inflammation | total saponins of Aralia elata (Miq.) Seem. | Biology (General)
    mesheuropmc: animal structures

Atherosclerosis is an arterial disease associated with inflammation. Hence, the discovery of novel therapeutic agents for suppressing inflammatory responses is urgent and vital for the treatment of atherosclerosis in cardiovascular diseases. The total saponins of Aralia... View more
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