Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects

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Blouin, C. M.; Le Lay, S.; Eberl, A.; Kofeler, H. C.; Guerrera, I. C.; Klein, C.; Le Liepvre, X.; Lasnier, F.; Bourron, O.; Gautier, J. F.; Ferre, P.; Hajduch, E.; Dugail, I.;
  • Publisher: The American Society for Biochemistry and Molecular Biology
  • Journal: The Journal of Lipid Research,volume 51,issue 5,pages945-956 (issn: 0022-2275, eissn: 1539-7262)
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  • Related identifiers: doi: 10.1194/jlr.M001016, pmc: PMC2853462
  • Subject: Research Article | triacylglycerol | phospholipids | lipid storage | obesity
    mesheuropmc: endocrine system | complex mixtures | eye diseases | lipids (amino acids, peptides, and proteins) | technology, industry, and agriculture

Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-1 deficiency on... View more
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