Acute toxicity of intravenously administered titanium dioxide nanoparticles in mice.

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Xu, Jiaying; Shi, Hongbo; Ruth, Magaye; Yu, Hongsheng; Lazar, Lissy; Zou, Baobo; Yang, Cui; Wu, Aiguo; Zhao, Jinshun;
(2013)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 8,issue 8 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3738549, doi: 10.1371/journal.pone.0070618
  • Subject: Toxicology | Biotechnology | Animal Models | Research Article | Biology | Materials Science | Veterinary Science | Veterinary Toxicology | Nanomaterials | Medicine | Mouse | Q | R | Histology | Model Organisms | Toxic Agents | Science | Nanotechnology | Veterinary Medicine | Bionanotechnology | Material by Attribute | Public Health

BACKGROUND: With a wide range of applications, titanium dioxide (TiO₂) nanoparticles (NPs) are manufactured worldwide in large quantities. Recently, in the field of nanomedicine, intravenous injection of TiO₂ nanoparticulate carriers directly into the bloodstream has ra... View more
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