publication . Other literature type . Article . 2016

Association between menopausal estrogen-only therapy and ovarian carcinoma risk

Daniel O. Stram; Anna H. Wu; Lynda D. Roman; Kathryn L. Terry; Michael E. Carney; Francesmary Modugno; Susan J. Ramus; Roberta B. Ness; Simon A. Gayther; Mary Anne Rossing; ...
Open Access English
  • Published: 01 May 2016
  • Country: United States
Abstract
OBJECTIVE: To describe the association between postmenopausal estrogen-only therapy use and risk of ovarian carcinoma, specifically with regard to disease histotype and duration and timing of use. METHODS: We conducted a pooled analysis of 906 women with ovarian carcinoma and 1,220 women in a control group; all 2,126 women included reported having had a hysterectomy. Ten population-based case-control studies participating in the Ovarian Cancer Association Consortium, an international consortium whose goal is to combine data from many studies with similar methods so reliable assessments of risk factors can be determined, were included. Self-reported questionnaire...
Subjects
Medical Subject Headings: female genital diseases and pregnancy complicationsendocrine system diseases
free text keywords: Article, Obstetrics and Gynaecology, General Medicine, Oncology, medicine.medical_specialty, medicine, Estrogen, medicine.drug_class, Internal medicine, Ovarian carcinoma, business.industry, business, Risk assessment, Population, education.field_of_study, education, Menopause, medicine.disease, Odds ratio, Gynecology, Hysterectomy, medicine.medical_treatment, Serous fluid, Ovarian cancer
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