mRNA transfection of mouse and human neural stem cell cultures.

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McLenachan, Samuel; Zhang, Dan; Palomo, A.B.; Edel, Michael John; Chen, Fred K.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 8,issue 12 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0083596, pmc: PMC3873397
  • Subject: Animal Models | Research Article | Molecular Cell Biology | Embryonic Stem Cells | Ratolins (Animals de laboratori) | Mice (Laboratory animals) | Neurons | Mouse | Neurones | Stem cells | Cellular Types | Biology | RNA | Neural Stem Cells | Developmental Biology | Medicine | Nucleic Acids | Adult Stem Cells | Q | R | Model Organisms | Science | Cèl·lules mare | Gene Expression
    mesheuropmc: fungi

The use of synthetic mRNA as an alternative gene delivery vector to traditional DNA-based constructs provides an effective method for inducing transient gene expression in cell cultures without genetic modification. Delivery of mRNA has been proposed as a safer alternat... View more
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