Subject: Chitosan | biomaterial | polycaprolactone | Microscopy, Electron, Scanning | electrophysiological procedures | Muscles | polyester | nerve fiber | extracellular space | Animals | Female | giant cell | scanning electron microscopy | Wistar rat | chemically induced | rat | peripheral nerve | nociception | drug effects | animal experiment | article | Motor Activity | Recovery of Function | Electrodiagnosis | animal | nonhuman | Biocompatible Materials | automutilation | adult | Research Article | pathology | tissue scaffold | nerve fiber regeneration | microenvironment | Axons | electrospinning | Inflammation | muscle | pathophysiology | procedures | Rats, Wistar | Nerve Regeneration | Article Subject | Tissue Scaffolds | freeze drying | Organ Size | foreign body reaction | in vivo study | electric field | Medicine | nerve transplantation | Foreign-Body Reaction | Polyesters | tissue regeneration | convalescence | R | controlled study | Pain Perception | Guided Tissue Regeneration | sciatic nerve
ddc: ddc:570 | ddc:610 | ddc:600
mesheuropmc: technology, industry, and agriculture | equipment and supplies
We report on the performance of composite nerve grafts with an inner 3D multichannel porous chitosan core and an outer electrospun polycaprolactone shell. The inner chitosan core provided multiple guidance channels for regrowing axons. To analyze the in vivo properties ... View more
Daly, W, Yao, L, Zeugolis, D, Windebank, A, Pandit, A. A biomaterials approach to peripheral nerve regeneration: bridging the peripheral nerve gap and enhancing functional recovery.
Journal of the Royal Society Interface
. 2012; 9 (67): 202-221