The Intriguing Regulators of Muscle Mass in Sarcopenia and Muscular Dystrophy

Article English OPEN
Sakuma, Kunihiro ; Aoi, Wataru ; Yamaguchi, Akihiko (2014)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Aging Neuroscience, volume 6 (issn: 1663-4365, eissn: 1663-4365)
  • Related identifiers: doi: 10.3389/fnagi.2014.00230/full, doi: 10.3389/fnagi.2014.00230, pmc: PMC4148637
  • Subject: Review Article | autophagy | Neurosciences. Biological psychiatry. Neuropsychiatry | RC321-571 | Neuroscience | myostatin | mTOR | serum rsponse factor | serum response factor | muscular dystrophies | sarcopenia
    mesheuropmc: human activities | musculoskeletal system

Recent advances in our understanding of the biology of muscle have led to new interest in the pharmacological treatment of muscle wasting. Loss of muscle mass and increased intramuscular fibrosis occur in both sarcopenia and muscular dystrophy. Several regulators (mamma... View more
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