The multidrug ABC transporter BmrC/BmrD of Bacillus subtilis is regulated via a ribosome-mediated transcriptional attenuation mechanism

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Reilman, Ewoud; Mars, Ruben A. T.; van Dijl, Jan Maarten; Denham, Emma L.;
(2014)
  • Publisher: Oxford University Press
  • Journal: Nucleic Acids Research, volume 42, issue 18, pages 11,393-11,407 (issn: 0305-1048, eissn: 1362-4962)
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  • Related identifiers: pmc: PMC4191407, doi: 10.1093/nar/gku832
  • Subject: IN-VIVO | TERMINATION | LEADER REGION | QR | Gene regulation, Chromatin and Epigenetics | ESCHERICHIA-COLI | GENE-EXPRESSION | CODON USAGE | INDUCTION | TRYPTOPHAN OPERON | DRUG-RESISTANCE | RNA-POLYMERASE | QP

Expression of particular drug transporters in response to antibiotic pressure is a critical element in the development of bacterial multidrug resistance, and represents a serious concern for human health. To obtain a better understanding of underlying regulatory mechani... View more
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