Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection

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Tweedy, Joshua ; Spyrou, Maria Alexandra ; Pearson, Max ; Lassner, Dirk ; Kuhl, Uwe ; Gompels, Ursula A. (2016)
  • Publisher: MDPI
  • Journal: Viruses, volume 8, issue 1 (issn: 1999-4915, eissn: 1999-4915)
  • Related identifiers: doi: 10.3390/v8010019, pmc: PMC4728579
  • Subject: CiHHV-6A | human herpesvirus | HHV-6A | virus genome | subtelomere | Microbiology | QR1-502 | Article | chromosomal integration | HHV-6 | telomeric repeats | CiHHV-6
    mesheuropmc: viruses

: Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated "CiHHV-6A/B". These affect approximately 1.0% of human populations, giving potential for virus gene e... View more
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