Vaccinia virus egress mediated by virus protein A36 is reliant on the F12 protein

Article English OPEN
Carpentier, David; Van Loggerenberg, A; Dieckmann, NMG; Smith, Geoffrey;
  • Publisher: Journal of General Virology
  • Journal: volume 98,issue 6,pages1,500-1,514issn: 0022-1317, eissn: 1465-2099
  • Related identifiers: pmc: PMC5656793, doi: 10.17863/CAM.12927, doi: 10.1099/jgv.0.000816
  • Subject: microtubule | proteins F12 and A36 | actin nucleation | Research Article | virus egress and spread | Large DNA Viruses | kinesin-1 | Animal | vaccinia virus
    mesheuropmc: viruses | macromolecular substances

Egress of vaccinia virus from its host cell is mediated by the microtubule-associated motor kinesin-1, and three viral proteins, A36 and the F12/E2 complex, have been implicated in this process. Deletion of F12 expression causes a more severe reduction in egress than de... View more
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