The Role of lysophosphatidic acide (LPA) in the insulin resistence of the pancreatic β-cells

Doctoral thesis German OPEN
Mourad Agha, Zein;
(2016)
  • Publisher: Freie Universität Berlin Universitätsbibliothek, Garystr. 39, 14195 Berlin
  • Subject: NO | Insulin | 540 Chemie und zugeordnete Wissenschaften | LPA | Insulinresistenz | β-Zellen | 540 Chemistry and allied sciences
    • ddc: ddc:540
    mesheuropmc: lipids (amino acids, peptides, and proteins)

The pathogenesis of the type-2-diabetes mellitus underlying is characterized by a combination of peripheral insulin resistance, β-cell dysfunction and reduction in the β cell mass. The increasing of FFA level or their metabolites lead to inhibition of insulin signaling.... View more
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