Mesenchymal stem cell-like properties of CD133+ glioblastoma initiating cells

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Pavon, Lorena Favaro; Sibov, Tatiana Tais; de Oliveira, Daniela Mara; Marti, Luciana C.; Cabral, Francisco Romero; de Souza, Jean Gabriel; Boufleur, Pamela; Malheiros, Suzana M.F.; de Paiva Neto, Manuel A.; da Cruz, Edgard Ferreira; Chudzinski-Tavassi, Ana Marisa; Cavalheiro, Sérgio;
  • Publisher: Impact Journals LLC
  • Journal: Oncotarget,volume 7,issue 26,pages40,546-40,557 (eissn: 1949-2553)
  • Related identifiers: pmc: PMC5130027, doi: 10.18632/oncotarget.9658
  • Subject: MSC immunophenotype | tumorigenesis in vivo | neurospheres | CD133+ | Research Paper | TEM
    mesheuropmc: carbohydrates (lipids) | biological phenomena, cell phenomena, and immunity | embryonic structures | fluids and secretions | neoplasms

Glioblastoma is composed of dividing tumor cells, stromal cells and tumor initiating CD133+ cells. Recent reports have discussed the origin of the glioblastoma CD133+ cells and their function in the tumor microenvironment. The present work sought to investigate the mult... View more
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