Modeling of Clostridium tyrobutyricum for Butyric Acid Selectivity in Continuous Fermentation

Article, Other literature type English OPEN
Du, Jianjun; McGraw, Amy; Hestekin, Jamie;
  • Publisher: Multidisciplinary Digital Publishing Institute
  • Journal: Energies (issn: 1996-1073)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.3390/en7042421
  • Subject: butyric acid | T | steady-state model | continuous fermentation | Clostridium tyrobutyricum | batch fermentation | <i>Clostridium tyrobutyricum</i> | Technology

A mathematical model was developed to describe batch and continuous fermentation of glucose to organic acids with Clostridium tyrobutyricum. A modified Monod equation was used to describe cell growth, and a Luedeking-Piret equation was used to describe the production of... View more
  • References (29)
    29 references, page 1 of 3

    1. Zigová, J.; Sturdik, E.; Vandak, D.; Schlosser, S. Butyric acid production by clostridium butyricum with integrated extraction and pertraction. Process Biochem. 1999, 34, 835-843.

    2. Vandak, D.; Zigová, J.; Sturdik, E.; Schlosser, S. Evaluation of solvent and pH for extractive fermentation of butyric acid. Process Biochem. 1997, 32, 245-251.

    3. Zhu, Y.; Yang, S.T. Adaptation of Clostridium tyrobutyricum for enhanced tolerance to butyric acid in a fibrous-bed bioreactor. Biotechnol. Prog. 2003, 19, 365-372.

    4. Ramey, D.E.; Yang, S.T. Production of Butyric Acid and Butanol from Biomass; Final Report to the US Department of Energy: Washington, DC, USA, 2004.

    5. Playne, M.J. Propionic and Butyric Acids. In Comprehensive Biotechnology: The Principles, Applications and Regulations of Biotechnology in Industry, Agriculture and Medicine; Moo-Young, M., Bull, A.T., Dalton, H., Cooney, C.L., Humphrey, A.E., Blanch, H.W., Drew, S., Wang, D.I.C., Robinson, C.W., Howell, J.A., Eds.; Pergamon Press: Oxford, England, UK, 1985; pp. 731-759.

    6. Alam, S.; Stevens, D.; Bajpai, R. Production of butyric acid by batch fermentation of cheese whey with Clostridium beijerinckii. J. Ind. Microbiol. Biotechnol. 1988, 2, 359-364.

    7. Crabbendam, P.M.; Neijssel, O.M.; Tempest, D.W. Metabolic and energetic aspects of the growth of Clostridium butyricum on glucose in chemostat culture. Arch. Microbiol. 1985, 142, 375-382.

    8. Papoutsakis, E.T. Equations and calculations for fermentations of butyric acid bacteria. Biotechnol. Bioeng. 1984, 26, 174-187.

    9. Heyndrickx, M.; de Vos, P.; de Ley, J. Fermentation of D-xylose by Clostridium butyricum LMG 1213t1 in chemostats. Enzyme Microb. Technol. 1991, 13, 893-897.

    10. Michel-Savin, D.; Marchal, R.; Vandecasteele, J.P. Butyrate production in continuous culture of Clostridium tyrobutyricum: Effect of end-product inhibition. Appl. Microbiol. Biotechnol. 1990, 33, 127-131.

  • Metrics
Share - Bookmark