Recombination-independent rapid convergent evolution of the gastric pathogen Helicobacter pylori

Article English OPEN
Chattopadhyay, Sujay; Chi, Peter B; Minin, Vladimir N; Berg, Douglas E; Sokurenko, Evgeni V;
(2018)
  • Publisher: BMC
  • Journal: BMC Genomics,volume 19 (issn: 1471-2164, eissn: 1471-2164)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC6249973, doi: 10.1186/s12864-018-5231-7
  • Subject: Helicobacter pylori | Information And Computing Sciences | Biotechnology | Research Article | Gastric pathogen | Adaptive evolution | Protein-coding genes | Biological Sciences | Medical And Health Sciences | Convergent mutations | QH426-470 | Genetics | Bioinformatics | TP248.13-248.65

Background Helicobacter pylori is a human stomach pathogen, naturally-competent for DNA uptake, and prone to homologous recombination. Extensive homoplasy (i.e., phylogenetically-unlinked identical variations) observed in H. pylori genes is considered a hallmark of such... View more
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