Spatiotemporal Dynamics of Dengue Epidemics, Southern Vietnam

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Cuong, Hoang Quoc ; Vu, Nguyen Thanh ; Cazelles, Bernard ; Boni, Maciej F. ; Thai, Khoa T.D. ; Rabaa, Maia A. ; Quang, Luong Chan ; Simmons, Cameron P. ; Huu, Tran Ngoc ; Anders, Katherine L. (2013)
  • Publisher: CENTERS DISEASE CONTROL
  • Journal: Emerging Infectious Diseases, volume 19, issue 6, pages 945-953 (issn: 1080-6059, eissn: 1080-6059)
  • Related identifiers: pmc: PMC3713821, doi: 10.3201/eid1906.121323
  • Subject: epidemiology | arthropod vectors | viruses | transmission | vector-borne infections | Vietnam | surveillance | Dengue | Research | heterogeneity | spatial distribution

textabstractAn improved understanding of heterogeneities in dengue virus transmission might provide insights into biological and ecologic drivers and facilitate predictions of the magnitude, timing, and location of future dengue epidemics. To investigate dengue dynamics in urban Ho Chi Minh City and neighboring rural provinces in Vietnam, we analyzed a 10-year monthly time series of dengue surveillance data from southern Vietnam. The per capita incidence of dengue was lower in Ho Chi Minh City than in most rural provinces; annual epidemics occurred 1-3 months later in Ho Chi Minh City than elsewhere. The timing and the magnitude of annual epidemics were significantly more correlated in nearby districts than in remote districts, suggesting that local biological and ecologic drivers operate at a scale of 50-100 km. Dengue incidence during the dry season accounted for 63% of variability in epidemic magnitude. These findings can aid the targeting of vector-control interventions and the planning for dengue vaccine implementation.