The Expression, Purification, and Characterization of a Ras Oncogene (Bras2) in Silkworm (Bombyx mori)

Article English OPEN
Lv, Zhengbing; Wang, Tao; Zhuang, Wenhua; Wang, Dan; Chen, Jian; Nie, Zuoming; Liu, Lili; Zhang, Wenping; Wang, Lisha; Wang, Deming; Wu, Xiangfu; Li, Jun; Qian, Lian; Zhang, Yaozhou;
(2013)
  • Publisher: Hindawi Publishing Corporation
  • Journal: International Journal of Genomics,volume 2,013 (issn: 2314-436X, eissn: 2314-4378)
  • Related identifiers: pmc: PMC3678442, doi: 10.1155/2013/269609
  • Subject: Research Article | Article Subject

The Ras oncogene of silkworm pupae (Bras2) may belong to the Ras superfamily. It shares 77% of its amino acid identity with teratocarcinoma oncogene 21 (TC21) related ras viral oncogene homolog-2 (R-Ras2) and possesses an identical core effector region. The mRNA of Bomb... View more
  • References (25)
    25 references, page 1 of 3

    Sun, P., Watanabe, H., Takano, K., Yokoyama, T., Fujisawa, J. I., Endo, T.. Sustained activation of M-Ras induced by nerve growth factor is essential for neuronal differentiation of PC12 cells. Genes to Cells. 2006; 11 (9): 1097-1113

    Blasco, R. B., Francoz, S., Santamaría, D., Cañamero, M., Dubus, P., Charron, J., Baccarini, M., Barbacid, M.. c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma. Cancer Cell. 2011; 19 (5): 652-663

    García-Silva, S., Martínez-Iglesias, O., Ruiz-Llorente, L., Aranda, A.. Thyroid hormone receptor β1 domains responsible for the antagonism with the ras oncogene: role of corepressors. Oncogene. 2011; 30 (7): 854-864

    Kennedy, A. L., Morton, J. P., Manoharan, I., Nelson, D. M., Jamieson, N. B., Pawlikowski, J. S., McBryan, T., Doyle, B., McKay, C., Oien, K. A., Enders, G. H., Zhang, R., Sansom, O. J., Adams, P. D.. Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis. Molecular Cell. 2011; 42 (1): 36-49

    Reuther, G. W., Der, C. J.. The Ras branch of small GTPases: Ras family members don't fall far from the tree. Current Opinion in Cell Biology. 2000; 12 (2): 157-165

    Ehrhardt, A., Ehrhardt, G. R. A., Guo, X., Schrader, J. W.. Ras and relatives—job sharing and networking keep an old family together. Experimental Hematology. 2002; 30 (10): 1089-1106

    Colicelli, J.. Human RAS superfamily proteins and related GTPases. Science's STKE. 2004; 2004 (250): RE13

    Wennerberg, K., Rossman, K. L., Der, C. J.. The Ras superfamily at a glance. Journal of Cell Science. 2005; 118 (5): 843-846

    Rosário, M., Paterson, H. F., Marshall, C. J.. Activation of the Ral and phosphatidylinositol 3′ kinase signaling pathways by the Ras-related protein TC21. Molecular and Cellular Biology. 2001; 21 (11): 3750-3762

    Gotoh, T., Niino, Y., Tokuda, M., Hatase, O., Nakamura, S., Matsuda, M., Hattori, S.. Activation of R-Ras by Ras-guanine nucleotide-releasing factor. Journal of Biological Chemistry. 1997; 272 (30): 18602-18607

  • Metrics
    No metrics available
Share - Bookmark