The Drosophila surface glia transcriptome: evolutionary conserved blood-brain barrier processes

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DeSalvo, Michael K.; Hindle, Samantha J.; Rusan, Zeid M.; Orng, Souvinh; Eddison, Mark; Halliwill, Kyle; Bainton, Roland J.;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Neuroscience,volume 8 (issn: 1662-453X, eissn: 1662-453X)
  • Related identifiers: doi: 10.3389/fnins.2014.00346, doi: 10.3389/fnins.2014.00346/full, pmc: PMC4224204
  • Subject: blood-brain barrier | genomics and evolution | surface glia | Neurosciences. Biological psychiatry. Neuropsychiatry | transcriptome | RC321-571 | CNS chemical protection processes | blood brain barrier | drosophila glia | Genetics | Original Research Article | Affymetrix array | drug partition
    mesheuropmc: cardiovascular system | nervous system

Central nervous system (CNS) function is dependent on the stringent regulation of metabolites, drugs, cells, and pathogens exposed to the CNS space. Cellular blood-brain barrier (BBB) structures are highly specific checkpoints governing entry and exit of all small molec... View more