Immunotherapy of Cancer: Reprogramming Tumor-Immune Crosstalk

Article, Review English OPEN
Payne, Kyle K. ; Toor, Amir A. ; Wang, Xiang-Yang ; Manjili, Masoud H. (2012)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Clinical and Developmental Immunology, volume 2,012 (issn: 1740-2522, eissn: 1740-2530)
  • Related identifiers: doi: 10.1155/2012/760965, pmc: PMC3477552
  • Subject: RC581-607 | Review Article | Immunologic diseases. Allergy | Article Subject
    mesheuropmc: chemical and pharmacologic phenomena

The advancement of cancer immunotherapy faces barriers which limit its efficacy. These include weak immunogenicity of the tumor, as well as immunosuppressive mechanisms which prevent effective antitumor immune responses. Recent studies suggest that aberrant expression o... View more
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