pH sensing and regulation in cancer

Article English OPEN
Mehdi eDamaghi; Jonathan W. Wojtkowiak; Robert J. Gillies;

Cells maintain intracellular pH (pHi) within a narrow range (7.1-7.2) by controlling membrane proton pumps and transporters whose activity is set by intra-cytoplasmic pH sensors. These sensors have the ability to recognize and induce cellular responses to maintain the ... View more
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