Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway

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Gutiérrez-Martínez, Enric; Fernández Ulibarri, Inés; Lázaro Diéguez, Francisco; Johannes, Ludger; Pyne, Susan; Sarri Plans, Elisabet; Egea Guri, Gustavo;
(2013)
  • Publisher: The Company of Biologists
  • Related identifiers: doi: 10.1242/jcs.117705
  • Subject: Homeostasis | Lípids | Lipids | Aparell de Golgi | Homeòstasi | Reticle endoplasmàtic | Golgi apparatus | Endoplasmic reticulum

The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport carriers at the Golgi and for retrograde trafficking to the ER. Here we report that the PAP2 family member lipid p... View more
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