Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs

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Ribas i Fortuny, Judit; Gómez Arbonés, Javier; Boix Torras, Jacint;
(2005)
  • Publisher: Elsevier
  • Related identifiers: doi: 10.1016/j.ejphar.2005.09.021
  • Subject: Cell cycle | Olomoucine | Apoptosi | Cicle cel·lular | Apoptosis | Caspases | Roscovitine

Olomoucine and Roscovitine are pharmacological inhibitors of cyclin-dependent kinases (CDK) displaying a promising profile as anticancer agents. Both compounds are effective inductors of apoptosis in a human neuroblastoma cell line, SH-SY5Y. The characterization of this... View more
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