Directional Connectivity between Frontal and Posterior Brain Regions Is Altered with Increasing Concentrations of Propofol

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Anu Maksimow; Minna Silfverhuth; Jaakko Långsjö; Kimmo Kaskinoro; Stefanos Georgiadis; Satu Jääskeläinen; Harry Scheinin;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 9, issue 11 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4242654, doi: 10.1371/journal.pone.0113616
  • Subject: Research Article | Biology and Life Sciences | Computer and Information Sciences | Anesthesiology | Neuroscience | Neural Networks | Medicine | Anesthesiology Technology | Anesthesiology Monitoring | Q | R | Science | Pharmacology | Medicine and Health Sciences | Anesthetic Mechanisms

Recent studies using electroencephalography (EEG) suggest that alteration of coherent activity between the anterior and posterior brain regions might be used as a neurophysiologic correlate of anesthetic-induced unconsciousness. One way to assess causal relationships be... View more
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