Replicative Stress Induces Intragenic Transcription of the ASE1 Gene that Negatively Regulates Ase1 Activity

Article, Other literature type English OPEN
McKnight, Kelly; Liu, Hong; Wang, Yanchang; (2014)
  • Publisher: Elsevier BV
  • Journal: Current Biology,volume 24,issue 10,pages1,101-1,106 (issn: 0960-9822)
  • Related identifiers: pmc: PMC4031280, doi: 10.1016/j.cub.2014.03.040
  • Subject: Agricultural and Biological Sciences(all) | Biochemistry, Genetics and Molecular Biology(all) | Article

Intragenic transcripts initiate within the coding region of a gene, thereby producing shorter mRNAs and proteins. Although intragenic transcripts are widely expressed [1], their role in the functional regulation of genes remains largely unknown. In budding yeast, DNA re... View more
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