Recent human evolution has shaped geographical differences in susceptibility to disease

Article English OPEN
Marigorta, Urko M; Lao, Oscar; Casals, Ferran; Calafell, Francesc; Morcillo-Suárez, Carlos; Faria, Rui; Bosch, Elena; Serra, François; Bertranpetit, Jaume; Dopazo, Hernán; Navarro, Arcadi;
(2011)
  • Publisher: BioMed Central
  • Journal: volume 12, issue 1, pages 55-55issn: 1471-2164, eissn: 1471-2164
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1186/1471-2164-12-55, handle: 10261/32965, pmc: PMC3039608
  • Subject: geographic distribution | Biotechnology | Evolució humana | Research Article | single nucleotide polymorphism | Caucasian | genetic association | Genètica mèdica | Chinese | QH426-470 | Genetics | geography | human | TP248.13-248.65 | gene replication | Genoma humà | Asian | disease predisposition | evolution | article | gene frequency | genetic variability | Negro | gene locus | controlled study | ethnic difference | ethnic group

<p>Abstract</p> <p>Background</p> <p>Searching for associations between genetic variants and complex diseases has been a very active area of research for over two decades. More than 51,000 potential associations have been studied and published, a figure that keeps incre... View more
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